GET UPDATED
Blog
WIDE OPEN AGRICULTURE
The WOA business model is a vertically integrated food and agriculture company comprising land assets, protected cropping and our food brand, Food for ReasonsTM.
We are seeking strong, sustainable financial returns and are committed to making a positive impact on the communities and ecosystems in which we operate. We are focused on improving biodiversity, enhancing soil health and creating new jobs and enterprises in Western Australia’s Wheatbelt. We want to become the world’s first listed company to deliver 4 Returns.
WOA Chairman Anthony Maslin, Managing Director Dr. Ben Cole and non-executive Director Stuart McAlpine will be conducting IPO Investor Presentations across the Wheatbelt and Australia in April and May 2018.
We hope as many local and global investors as possible choose to participate in the Offer. We believe that real change comes through people coming together and striving for a better world. Buying shares in WOA is a statement of your belief that regenerative, diversified farming systems can deliver great outcomes.
WOA’s incredible journey now hits Perth kicking off with an event at Scarborough’s The Art Space Collective tonight!
Tomorrow, we’re at Fremantle’s PS Art Space with Guest Speaker, the honorable Alannah MacTiernan! Thanks Minister.
Thursday we’re at Perth City Farm Another fantastic venue!
We’ve been inundated with interest and we’re expecting big numbers at all events! To register for the free events, go to:
www.wideopenagriculture.com.au
...where you can also download your prospectus and apply for shares!
WOA’s philosophy is based on four returns:
Environmental
Financial
Social and
The return of new hope and inspiration to people and places that need it most!
Venues for IPO Roadshow
Wheatbelt
No registration necessary
Moora Tuesday, 17/4/18 at 12.30pm - Drovers Inn, 1 Dandaragan St, Moora
Dalwallinu Tuesday, 17/4/18 at 6pm - Dalwallinu Sports Club,Colin Anderson Drive, Dalwallinu
Goomalling Wednesday 18/4/18 at 12.30pm - Goomalling Tavern, 61 Railway Tce, Goomalling
Merredin Wednesday 18/4/18 at 6pm - Cummins Theatre (Tivoli Room) 31 Bates St, Merredin
Narrogin Thursday 19/4/18 at 12.30pm - Duke of York Hotel, 34 Federal St, Narrogin
Williams Thursday 19/4/18 at 6pm - Williams Hotel, 26 Albany Hwy, Williams
Perth
For Perth events please register your RSVP below:
Monday, 23 April at 6pm Scarborough
Tuesday, 24 April at 6pm Fremantle
Thursday, 26 April at 6pm Perth City Farm
Email info@wideopenagriculture.com.au
STRUCTURAL MONITORING SYSTEMS EXECUTES WORLD’S FIRST COMMERCIAL SUPPLY & MARKETING AGREEMENT
WITH DELTA AIR LINES
17th August 2017
HIGHLIGHTS:
- SMS executes pivotal Aircraft Component Purchase (“ACP”) Agreement with Delta Air Lines, Inc.
- The Agreement is non-exclusive, and is for a 10-year term, with rolling 10-year extension provisions, as agreed at outset by both Parties
- Delta and SMS fully aligned to identify, and gain OEM/Regulator approval for, multiple applications on all aircraft types across the entire Delta fleet
- In-aircraft applications will be approved for CVM™ via OEM issued Service Bulletin (“SB”) Revisions and/or Regulator mandated Airworthiness Directive (“AD”) Global Alternative Means of Compliance (“AMOCs”). Thus, CVM™ to receive global installation approval - from both OEMs and Regulators - enabling unfettered adoption across all the world’s commercial airline fleets
- Delta TechOps to evaluate the provision of CVM™ installations to its key airline carrier customers, namely Delta Complete Fleet™ Services customers. TechOps, based in Atlanta, GA, is the largest airline maintenance, repair and overhaul facility (“MRO”) in North America, and third largest in the world
Structural Monitoring Systems plc (“SMS” or “the Company”) (ASX: SMN) is extremely pleased to announce that it has executed the world’s first commercial agreement related to the supply and permitted use of a structural health monitoring (“SHM”) technology with a commercial airline operator.
SMS and Delta Air Lines, Inc. (“Delta”), have formalised a critical, strategic commercial relationship through the execution of an Aircraft Component Purchase (“ACP”) Agreement (“the Agreement”).
The Company is pleased to provide a brief summary of some of the key commercial terms, benefits and outcomes of this Agreement including, but not limited to, the following:
- Delta will partner with SMS to identify multiple CVM applications. on multiple aircraft types, across Delta’s entire mainline aircraft fleet
- The Agreement is non-exclusive, and is for a 10-year term, with rolling 10-year extension provisions, as agreed at outset by both Parties
- Delta permitted to purchase CVM™ sensors, hardware and related peripheral equipment at a discount to the SMS global catalogue list prices paid by Delta competitors
- Through the purchase of an initial threshold level of CVM™ equipment, Delta will earn the right to receive commissions on all SMS sales of CVM™ equipment, and technology license agreements, transacted with global airline operators. The approximate revenue value associated with these initial threshold sales of CVM™ equipment to Delta is expected to be in the vicinity of $US6-7 million
A major global carrier’s adoption and fleet-wide installation of CVM™ technology, would lead the global commercial aviation sector to full, widespread use of CVM™ products. Subsequent sales of CVM™-related equipment to the world’s remaining airline carrier fleets would be expected to generate revenues that are many multiples higher than those revenues generated with Delta - and this excludes the per annum revenue value that would be derived from annual, continuously renewable CVM™ technology licensing agreements. The commercial value of technology license agreements will ultimately peak at approximately $US10-15 million, on a per annum/per operator basis, for a typical Tier I airline operator.
As a direct result of the Agreement, SMS expects material revenue growth across its platform of products in the future. Importantly, due to the Company’s extremely high operating leverage, SMS also similarly operates at an extremely high revenue margin. This is due to a number of contributing factors, including, but not limited to:
- Sensor production volume is highly scalable with the addition of low-cost/high-output, laser cutting machines
- Current production facilities have material, embedded excess capacity. Thus, significant output increases can be realised with negligible effect on direct operating costs and total overhead
- The likelihood of a third-party, high profile organisation completing on-site airline operator installations, training and support in the future - with limited input required from SMS and/or AEM personnel. SMS already has an MoU agreement in place with Testia, an Airbus Group Company –that is highly suited to performing such a role
Commenting on the Agreement, SMS Chief Executive Officer, Toby Chandler, stated:
“We are extremely pleased to have now executed what is undoubtedly the world’s most significant Agreement in the burgeoning field of Structural Health Monitoring with Delta Air Lines.
“We have worked with Delta for a long time to finally achieve this extremely important “company-making” milestone Agreement. As SMS has matured into a progressive and rapidly evolving technology company, we are extremely fortunate to have such a high-profile, commercially powerful and globally-recognised partner to accelerate CVM™ into the commercial realm.
“SMS has now well and truly “arrived”, and the Company enjoys a very visible, and substantial, “first-mover” advantage coupled with a unique and highly disruptive technology; we intend to exploit these clear commercial advantages to their fullest.
“I would like to sincerely thank all of our team at SMS and AEM, and all related personnel from Delta, Sandia Labs, and other contributing organisations, for their focus and efforts. We now look forward to realising CVM™’s true commercial potential in the global civilian aerospace arena, and creating a demonstrably valuable business for SMS shareholders, and for our friends and colleagues at Delta, who join us as a highly regarded, and valued, strategic partner.
“Finally, I would like to thank our shareholders and supporters who have ridden out a complex and lengthy period of contractual development and negotiation.”
On behalf of Delta Air Lines, David Piotrowski, Senior Engineer, Delta Tech Ops, further noted:
“Delta TechOps looks forward to incorporating the use of CVM™ technology across the Delta fleet to help us maintain our aircraft in a more cost-efficient, and time-efficient, manner. We firmly
believe that SHM is the next level of non-destructive testing (“NDT”), and the commercial relationship we have cemented with this Agreement advances and elevates our investment in,
and commitment to, SMS’s CVM™ technology as the clear industry leader in this game-changing field. We look forward to a close and highly productive association for years to come”.
Adding further input from SMS’s key advisor, and long-term partner, Sandia Laboratories, Dr Dennis Roach, Head of the FAA Airworthiness and Assurance Centre, commented:
“We have been conducting laboratory and flight testing of CVM™ sensors for almost 15 years and with SMS’s technology we have finally confirmed a performance benchmark that can meet current crack detection requirements. In addition, the CVM™ monitoring hardware produces a turnkey system, and a holistic solution, that can be incorporated – with highly favorable results –
into current aircraft maintenance environments. As a result, CVM™ is currently the most commercially-ready technology, and the only Structural Health Monitoring (“SHM”) solution that has a demonstrated, advanced Technology Readiness Level of 9, indicating it is industry-proven and ready for deployment.
“The CVM™ technology has moved through multiple review and approval processes and is the first SHM method to achieve approval for routine use on commercial aircraft. Critically, as multiple aircraft manufacturers move through their final stages of technology validation, CVM™ holds a significant “market leader” position, and embodies tremendous promise for in-situ monitoring of all aircraft types, as well as other structures in numerous industries beyond aerospace.
“With this Agreement, the next step toward global use of CVM™ systems - across multiple applications - is now well underway with a number of aerospace OEMs and airlines.”
All staff at SMS, and AEM, are looking forward to the months ahead as we work towards executing the multiple commercial platform opportunities provided through the new relationship with Delta – as well as those that will develop through the new strategic relationships that this alliance will foster. The Company also looks forward to the continued development and execution of all SMS’s valuable legacy programmes in the civil aerospace, military and rotor-craft sectors.
The Company will host an investor conference call to be held Wednesday, August 23rd, 2017 at 11.00am AEST. Call details and format will be updated via separate forthcoming ASX announcement.
For further details please contact:
|
|
______________________________________________________________________________________________________________________
DOUBLE MAGIC – Exploration Update
large Magmatic Ni-Cu mineralised System confirmed
16th August 2017
- Twelve of the 13 holes drilled so far have intersected visible sulphides within Ruins Dolerite
- Multiple zones of interpreted primary Ni-Cu sulphides intersected within mafic-ultramafic rocks, confirming the presence of a large, complex magmatic Ni-Cu sulphide system at Merlin
- Sulphides in drillholes now identified along 1,500m of strike and down 500m of dip, open in all directions
- High power DHTEM survey contractors due on-site tomorrow
- First two batches of samples have been dispatched for laboratory analysis, results expected within 3 weeks
- Drilling is ongoing
- Source of large Induced Polarization (IP) chargeability anomaly still undetermined
- Excellent results from preliminary metallurgical flotation testwork
- First flora and fauna baseline survey completed
Buxton Resources Limited (ASX: BUX & BUXO) is pleased to provide an update on exploration completed at the Double Magic project since mid July. Work is ongoing. Drilling at Merlin is progressing steadily, with nearly half of planned holes completed. Step-out results are strongly positive confirming mostly disseminated, persistent, visible Ni-Cu sulphide mineralisation along strike and down-dip from the 2015 discovery holes at Conductor D. Buxton advises readers that sulphides can be visible in trace amounts or greater.
Drilling has now tested approximately 1,500 metres of strike extent and over 500 metres of dip extent at Merlin, with visible sulphide mineralisation in multiple horizons still open in all directions. See Figure 1 for the current drillhole location plan.
Significantly, a second mineralised horizon within the same Ruins Dolerite package has been identified about 100m below the first zone discovered in 2015. Some holes have now intersected three or more discrete zones of visible sulphides within a range of rock-types, highlighting the complexity to be expected within multi-phase mafic-ultramafic intrusive bodies such as the Ruins Dolerite. The pervasive nature of sulphide mineralisation being discovered at Merlin is best illustrated by the fact that of the 13 holes drilled so far in 2017, all but one have intersected visible sulphides, all within rocks assigned to the Ruins Dolerite, predominantly meta-dolerite and meta-pyroxenite, the latter with characteristics of a cumulate rock, a very positive genetic indicator in systems such as these.
Sulphides are typically fine to coarse disseminated pyrrhotite and chalcopyrite, with pentlandite and pyrite also likely to be present (assays pending). Heavily disseminated zones of interstitial (interpreted to be magmatic) sulphides occur for example in DMDD0006, 100m down dip from 2015 discovery holes at Conductor D, with 9.5m of strongly disseminated to weakly net textured sulphides from 106m down-hole (see Figure 2).

Figure 1 - Plan of previous and 2017 drillhole locations
Figure 2 Net-textured sulphides in DMDD0006, 108.9m down-hole, quarter-core shown
Some of the remobilisation of sulphides noted in chips and particularly core may reflect later-stage magmatic activity related to primary mineralisation, while in other areas higher-level hydrothermal processes likely unrelated to primary mineralisation, are clearly evident.
Two RC holes and one diamond hole have been drilled through the two main >30mV/V Induced Polarisation chargeability isoshells, two holes (DMRC0026, DMDD0005) in the main western anomaly and one hole (DMRC0030) in a second isoshell to the south-east of Jack’s Hill. None of these holes intersected anything observable in chips or core which could account for the IP anomaly, however the two western holes continued to depth testing geological targets. Both subsequently intersected sulphides within Ruins Dolerite well below the chargeability anomaly. Down-hole chargeability and benchtop testwork will be completed within coming weeks to determine the source of the chargeability anomaly.
For details of drillhole locations and a summary of visible sulphide intersections greater than 5 metres in down-hole length, see Tables 2 and 3 at the end of this document. For the general location of Buxton’s Double Magic project, see Figure 3 also at the end of this document.
High Power Down-hole TEM survey to commence
Wireline Services Group is currently enroute to site to complete the first round of high-power down-hole TEM (DHTEM) surveys on all holes drilled to date. All holes will also be gyro-surveyed, with other electrical logging to be trialled on selected holes. Results are expected over the next 2-3 weeks. Buxton considers DHTEM an essential targeting tool at Merlin, with timely receipt of results during drilling a critical success factor.
Assay Results
Several batches of samples are being freighted to Perth for laboratory analysis. Results are expected within 3 to 4 weeks.
Metallurgical Testwork
Buxton has received results from preliminary metallurgical testwork conducted on selected diamond drill core from 2015 holes DMDD0001 and DMDD0003. Three 12 kg core samples grading 1.82% Ni, 3.17% Ni and 0.55% Ni respectively were submitted for batch froth flotation analysis by ALS laboratory in Perth.
Results are outstanding with excellent recoveries from the relatively course grind size of 106µm (0.106mm). Grind power requirements appear typical of WA nickel operations. Upside is considered likely on all these results as the test regime applied was a standard, non-optimised “sighting” process. Further metallurgical work will be undertaken later this year. See Table 1 for full results.
Table 1: Metallurgical test work details
Sample # |
Sample type |
Ni% Head Grade |
Recovery Ni% |
Cu% Head Grade |
Recovery Cu% |
Co% Head Grade |
Recovery Co% |
Grind Size |
|
DM_Met#1 |
Mixture of disseminated and net textured |
1.82% |
94% |
0.51% |
99% |
0.06% |
88% |
106µm |
|
DM_Met#2 |
Net textured Mineralisation |
3.17% |
95% |
0.90% |
98% |
0.10% |
92% |
106µm |
|
DM-Met#3 |
Disseminated Mineralisation |
0.55% |
79% |
0.26% |
91% |
0.024% |
60% |
106µm |
|
Flora and Fauna Study
During July Ecologica Environment completed an inaugural flora and fauna survey around the Merlin area. This survey was an “end of Wet season” baseline survey undertaken by a botanist and a zoologist, and was focused on identification of various flora and fauna within the project area.
Table 2: 2017 Drillhole Location Details |
|||||||||
hole type |
Hole_ID |
Easting |
Northing |
RL |
azimuth |
Inclination |
EOH depth |
||
Diamond |
DMDD0005 |
655035 |
8126878 |
95 |
35 |
-80 |
434.4 |
||
Diamond |
DMDD0006 |
655431 |
8127068 |
106 |
35 |
-60 |
150.4 |
||
Diamond |
DMDD0007 |
655202 |
8127111 |
104 |
35 |
-60 |
261 |
||
RC |
DMRC0025 |
655152 |
8127039 |
96 |
35 |
-80 |
316 |
||
RC |
DMRC0026 |
654881 |
8127007 |
90 |
360 |
-90 |
385 |
||
RC |
DMRC0027 |
655351 |
8127091 |
103 |
35 |
-60 |
258 |
||
RC |
DMRC0028 |
655598 |
8127139 |
108 |
35 |
-60 |
132 |
||
RC |
DMRC0029 |
655147 |
8127224 |
155 |
35 |
-60 |
234 |
||
RC |
DMRC0030 |
656240 |
8126351 |
102 |
35 |
-60 |
240 |
||
RC |
DMRC0031 |
655072 |
8126719 |
99 |
35 |
-60 |
306 |
||
RC |
DMRC0032 |
654954 |
8127104 |
93 |
35 |
-60 |
265 |
||
RC |
DMRC0033 |
655490 |
8127151 |
117 |
35 |
-60 |
90 |
||
RC |
DMRC0034 |
655387 |
8127255 |
154 |
35 |
-60 |
78 |
Table 3: Visible sulphide intersections greater than 5 metres down-hole length |
|
||||||||
Hole_ID |
Easting |
Northing |
RL |
azimuth |
dip |
From |
To |
DH Length |
|
DMDD0005 |
655035 |
8126878 |
95 |
35 |
-80 |
303.8 |
310.55 |
6.75 |
|
313.3 |
320.7 |
7.4 |
|||||||
322.9 |
328.7 |
5.8 |
|||||||
346.65 |
358.85 |
12.2 |
|||||||
361.6 |
369.8 |
8.2 |
|||||||
375.4 |
434.4 |
59 |
|||||||
DMDD0006 |
655431 |
8127068 |
106 |
35 |
-60 |
32 |
45.1 |
13.1 |
|
57.4 |
90.4 |
33 |
|||||||
106 |
115.5 |
9.5 |
|||||||
DMDD0007 |
655202 |
8127111 |
104 |
35 |
-60 |
57 |
67 |
10 |
|
178 |
184.6 |
6.6 |
|||||||
DMRC0025 |
655152 |
8127039 |
96 |
35 |
-80 |
250 |
259 |
9 |
|
DMRC0026 |
654881 |
8127007 |
90 |
360 |
-90 |
298 |
306 |
8 |
|
DMRC0027 |
655351 |
8127091 |
103 |
35 |
-60 |
83 |
95 |
12 |
|
215 |
220 |
5 |
|||||||
DMRC0028 |
655598 |
8127139 |
108 |
35 |
-60 |
67 |
76 |
9 |
|
DMRC0029 |
655147 |
8127224 |
155 |
35 |
-60 |
178 |
184 |
6 |
|
DMRC0030 |
656240 |
8126351 |
102 |
35 |
-60 |
No visible sulphides |
|||
DMRC0031 |
655072 |
8126719 |
99 |
35 |
-60 |
148 |
155 |
7 |
|
170 |
178 |
8 |
|||||||
191 |
200 |
9 |
|||||||
217 |
226 |
9 |
|||||||
245 |
254 |
9 |
|||||||
DMRC0032 |
654954 |
8127104 |
93 |
35 |
-60 |
114 |
122 |
8 |
|
DMRC0033 |
655490 |
8127151 |
117 |
35 |
-60 |
51 |
57 |
6 |
|
DMRC0034 |
655387 |
8127255 |
154 |
120 |
-60 |
16 |
34 |
18 |
|
Figure 3 – Location of the Double Magic Ni-Cu Project in Western Australia. Also shown is the location of Panoramic’s Savannah Ni-Cu Mine.
Buxton looks forward to progressively updating investors in coming weeks and months as results come to hand. For further information regarding Buxton Resources Limited please contact:
Sam Wright
Company Secretary
sam@buxtonresources.com.au
Competent Persons
The information in this report that relates to Exploration Results is based on information compiled by Mr Rolf Forster, Member of the Australasian Institute of Mining and Metallurgy, and Mr Eamon Hannon, Fellow of the Australasian Institute of Mining and Metallurgy. Mr Forster is an Independent Consultant to Buxton Resources Limited and Mr Hannon is an employee and Director. Mr Forster and Mr Hannon have sufficient experience which is relevant to the activity being undertaken to qualify as a “Competent Person”, as defined in the 2012 edition of the Joint Ore Reserves Committee (JORC) Australasian Code for Reporting of Exploration Results, Mineral Resources and Ore Reserves. Mr Forster and Mr Hannon consent to the inclusion in this report of the matters based on the information in the form and context in which it appears.
_______________________________________________________________________________________________________________________
DOUBLE MAGIC NI-CU PROJECT – RC Drilling COmmenced
13th July 2017
- Reverse Circulation (RC) drill rig on site, drilling has commenced
- Diamond Drilling (DD) drill rig expected on site this week
- Forthcoming work program set to fully test extents of the Merlin Ni-Cu mineralised system, with up to 10,000 metres of drilling
- Samples will be batched for laboratory submission, assay results will be received systematically in blocks during drilling
- High power DHTEM will be completed routinely on every hole
- At the Fireant prospect, detailed mapping and sampling was completed during June
Buxton Resources Limited (ASX: BUX) is pleased to advise that the Reverse Circulation (RC) drill rig and crew has arrived and established safely onsite at the Double Magic project, Merlin prospect. RC drilling commenced yesterday, 9th July 2017. An HQ diamond core drilling rig is scheduled to be on site and drilling later this week. For location of the Double Magic project, see Figure 1 at the end of this announcement.
Buxton’s 2015 discovery of high-grade primary magmatic nickel-copper sulphides at Double Magic (Merlin prospect) confirmed better than economic grades and thicknesses for the first time in the region. Widespread, near-surface >1% Ni sulphide mineralisation was intersected, with >3% Ni assays returned from three separate targets within the 3 km2 Merlin prospect (ASX 27/11/15). This marked a historic turning point for mineral exploration in the West Kimberley.
The first two phases of drilling at Merlin were completed by September 2015. During 2016 Buxton de-risked future drilling by completing extensive further technical work and specialist studies, notably including an innovative high power pseudo-3D Induced Polarisation (IP) survey (ASX 24/10/16).
After a prolonged 2016-17 Wet season, Buxton has re-established site access and drilling has now begun at Merlin with up to 10,000m of both RC and DD from circa 30 holes to be completed. Drill targets fall into three distinct but often overlapping categories;
- Step-out drilling around open, near-surface mineralisation identified by the 2015 drilling;
- Testing down-dip extensions of the 700m continuous zone of primary Ni-Cu sulphides identified in outcrop during 2016 (ASX 2/11/16)
- Testing deeper or conceptual geological and geophysical targets, including the large IP chargeability anomaly identified by Buxton in 2016.
Importantly, all EM conductors (airborne, surface and down-hole) drill tested to date at Merlin have proven to be related to nickel-copper sulphide mineralisation. Two 2015 holes also clipped the edge of the 2016 IP chargeability anomaly, these holes also intersected disseminated, magmatic Ni-Cu sulphides in prospective igneous mafic rocks.
Coupled with sulphide mineralisation in outcrop in two locations and the numerous, widespread high-grade Ni-Cu intersections in 2015 drilling (see Figure 2 below), Buxton is confident that the Merlin prospect represents a large, previously unknown magmatic Ni-Cu sulphide system. The 2017 program beginning now is designed to explore within that system.
As a routine part of the drill program, gyro surveys will be conducted on all holes as well as high-power down-hole TEM (DHTEM) surveys. Drill samples will be submitted routinely in batches to laboratories in Perth. Significant assay results will be reported as they come to hand. Additional market updates will also be issued as required.
Figure 2 – Simplified geology, geophysical responses, and previously reported 2015 drillhole intersections, Merlin Prospect
As part of mapping and sampling completed during June at the Fireant prospect 15km to the east, several geophysical (VTEM) drill targets were upgraded in prospectivity. Large volumes of prospective igneous mafic rocks have now been outlined at Fireant. Traces of fine disseminated sulphides were seen in rocks prospective for magmatic sulphide systems, updip of several modelled VTEM conductor plates. A seventh combined geological and geophysical target was also added to the initial six Fireant conductors selected for drill testing, planned to be one initial hole per target.
Buxton looks forward to updating investors again soon during this exciting stage of work at Double Magic.
Figure 1 – Location of the Double Magic Ni-Cu Project in Western Australia. Also shown is the location of Panoramic’s Savannah Ni-Cu Mine.
For further information regarding Buxton Resources Limited please contact:
Sam Wright
Company Secretary
sam@buxtonresources.com.au
Competent Persons
The information in this report that relates to Exploration Results is based on information compiled by Mr Rolf Forster, Member of the Australasian Institute of Mining and Metallurgy, and Mr Eamon Hannon, Fellow of the Australasian Institute of Mining and Metallurgy. Mr Forster is an Independent Consultant to Buxton Resources Limited and Mr Hannon is an employee and Director. Mr Forster and Mr Hannon have sufficient experience which is relevant to the activity being undertaken to qualify as a “Competent Person”, as defined in the 2012 edition of the Joint Ore Reserves Committee (JORC) Australasian Code for Reporting of Exploration Results, Mineral Resources and Ore Reserves. Mr Forster and Mr Hannon consent to the inclusion in this report of the matters based on the information in the form and context in which it appears.
PHASE II CANINE TRIAL BEGINS AT THE UNIVERSITY OF CAMBRIDGE
September 19, 2016
First canine treated with reformulated MPL in capsules
The primary objective of the trial is to examine the effects of reformulated MPL capsules in different canine cancers with the aim of determining which cancers should be targeted in Phase III.
The canines in this study will have failed “standard of care” and will have few or no therapeutic options available. The Phase I canine trial undertaken in 2014/2015 showed excellent safety with suppression of tumour markers and the current Phase II is intended to build on these successful earlier results by including determinations of regression, stable disease or progression by measurement of tumour size.
The ease with which owners can administer MPL capsules will also be an important factor in the trial as the initial phase I trial was limited by palatability issues of the drug, which led to the development and manufacture of the capsules.
PharmAust’s Chairman, Dr Roger Aston said: “Having initially demonstrated activity against cancer in man and canines, this Phase II study in dogs is a critical step as it is intended to show clinically relevant endpoints such as tumour size and growth or regression. Furthermore, a positive effect in canines will be a strong indication as to what can be expected in man. It is also noteworthy that most canine cancer drugs are essentially the same as those used in man with a modified dose.”
As MPL is already approved for veterinary use by PharmAust’s partner, Novartis Animal Health, we believe that if successful in this trial, MPL will be able to be approved quickly for the treatment of dog cancers following a further pivotal study.
We look forward to reporting progress when further animals are recruited and treated.